The package provide a list of known hotspot positions located on the amplicons of the Ion AmpliSeq<e2><84><a2> Colon and Lung Cancer Panel v2 as a txt file
hotspot.txt which contains a vector/variable —named chrpos (first row)— of chars, of the form chrN:XXXXXXXXX defining genomic positions.
N. P<c3><a9>cuchet, P. Laurent-Puig and Y. Rozenholc
Analysis of base-position error rate of next-generation sequencing to detect tumor mutations in circulating DNA N. P<c3><a9>cuchet, Y. Rozenholc, E. Zonta, D. Pietraz, A. Didelot, P. Combe, L. Gibault, J-B. Bachet, V. Taly, E. Fabre, H. Blons, P. Laurent-Puig in Clinical Chemistry
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