cppPoD: Probability of disease calculation

In PoDBAY: Vaccine Efficacy Estimation Package

Description

Function calculates probability of disease (PoD) for given titers according to a PoD curve.

Usage

cppPoD(titer, pmax, et50, slope, adjustTiters = FALSE, adjustFrom = 0, adjustTo = 0)

Arguments

titer	numeric vector: vector of subject level titers
pmax	numeric: maximum PoD
et50	numeric: titer value corresponding to pmax/2 value, PoD(et50) = pmax/2
slope	numeric: slope of the PoD curve
adjustTiters	boolean: set to TRUE if titer values should be adjusted, for details see PoD function
adjustFrom	numeric: value specifying the detection limit, all values below the detection limit will be adjusted to adjustTo value
adjustTo	numeric: value to which titers below the detection limit will be adjusted

Details

See PoD function for more details. These two functions are equivalent. Usage of cppPoD significantly improves the computation speed over the PoD function.

Value

vector of PoDs

PoDBAY documentation built on Sept. 21, 2021, 5:08 p.m.