High level function to perform random walk with restart cross-validation experiments with multiple classes.

1 2 |

`gamma` |
restart parameter (def: 0.6) |

`tmax` |
maximum number of iterations (def: 1000) |

`eps` |
maximum allowed difference between the computed probabilities at the steady state (def. 1e-10) |

`k` |
number of folds for the cross validation (def. 5) |

`filter` |
if TRUE (def) the adjacency matrix is sparsified otherwise not |

`seed` |
seed of the random generator for the generation of the folds (def: 1) |

`data` |
name of the data set to loaded (without rda extension). It must be an .rda file containing the adjiacency matrix of the graph. It assumes that it is in the "data" directory |

`labels` |
name of the target labels (without rda extension). It must be an .rda file containing the label matrix of the examples. It assumes that it is in the "data" directory |

High level function to perform cross-validation experiments with multiple classes using RWR.

It performs a k fold CV on a given data set, and output scores, AUC and Precision at a given recall results for multiple classes.

Graph data are read from a matrix representing the adjiacency matrix of the graph stored as a .rda file. The labels are read from a matrix having examples as rows and classes as columns stored as a .rda file. If *M* is the label matrix, then *M[i,j]=1*, if example *i* is annotated with class *j*, otherwise *M[i,j] = 0*.

Results are included in matrices representing Scores, AUC and precision at a given recall results stored as .rda files.

3 rda files stored in the output.dir directory:

`Scores results` |
A matrix with examples on rows and classes on columns representing the computed scores for each example and for each considered class |

`AUC results` |
AUC results files computed through |

`Precision at given recall results` |
computed through |

The name of the Score file starts with Score, of the AUC file with AUC, and of the Precision at given recall file with PXR. Other learning parameters are appended to the name of the file. All the results .rda files are stored in the Results directory (that must exist in advance).

`RWR`

, `multiple.RW.cv`

, `do.RW`

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 | ```
## Not run:
# Yeast prediction of 177 FunCat classes by 5-fold cross validation
# using 3 steps of Random walk with restart and STRING data.
# data obtained from the bionetdata package from CRAN
# See the AUC and Precision/recall results in the Results directory
library(bionetdata);
if (!dir.exists("data"))
dir.create("data");
if (!dir.exists("Results"))
dir.create("Results");
data(Yeast.STRING.data);
data(Yeast.STRING.FunCat);
save(Yeast.STRING.data, file="data/net.rda");
save(Yeast.STRING.FunCat, file="data/labels.rda");
do.RWR(tmax = 3, k = 5, filter = FALSE, seed = 1, data="net", labels="labels");
# the same experiment, but the iterations are repeated till to convergence
# (this can require a quite long time ...)
do.RWR(tmax = 1000, k = 5, eps = 1e-5, filter = FALSE, seed = 1, data="net", labels="labels");
## End(Not run)
``` |

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