model.pk: Generate trajectory of PK model

In REMixed: Regularized Estimation in Mixed Effect Model

Generate trajectory of PK model

Description

The administration is via a bolus. The PK model has one compartment (volume V) and a linear elimination (clearance Cl). The parameter ka is defined as ka=\frac{Cl}{V}.

Usage

model.pk(t, y, parms)

Arguments

t	vector of time ;
y	initial condition, named vector of form c(C=C0) ;
parms	named vector of model parameter ; should contain either "Cl" and "V" or "ka".

Value

Matrix of time and observation of Concentration C.

See Also

indParm.

Examples

res <- model.pk(seq(0,30,1),c(C=100),parms=c(ka=1))

plot(res)

REMixed documentation built on June 28, 2025, 1:09 a.m.