computeAUC: computeAUC: computes AUC
In RadioGx: Analysis of Large-Scale Radio-Genomic Data

Description Usage Arguments Details Examples

This function computes the area under a dose-response curve of the form survival fraction SF = exp(-alpha * D - beta * D ^ 2).

1 2	computeAUC(D, SF, pars, lower, upper, trunc = TRUE, SF_as_log = FALSE, area.type = c("Fitted", "Actual"), verbose = TRUE)

`D`	vector of dosages
`SF`	vector of survival fractions
`pars`	parameters (alpha, beta) in equation y = exp(-alpha * x - beta * x ^ 2)
`lower`	lower bound of dose region to compute AUC over
`upper`	upper bound of dose region to compute AUC over
`trunc`	should survival fractions be truncated downward to 1 if they exceed 1?
`SF_as_log`	A boolean indicating whether survival fraction is displayed on a log axis. Defaults to FALSE
`area.type`	should the AUC of the raw (D, SF) points be returned, or should the AUC of a curve fit to said points be returned instead?
`verbose`	how detailed should error and warning messages be? See details.

If lower and/or upper are missing, the function assumes their values to be the minimum and maximum D-values, respectively. For all warnings to be silent, set trunc = FALSE. For warnings to be output, set trunc = TRUE. For warnings to be output along with the arguments that triggered them, set trunc = 2.