Get_Resampling_Pvalue: Compute a resampling p-value

In SKAT: SNP-Set (Sequence) Kernel Association Test

Compute a resampling p-value

Description

Compute a resampling p-value using resampled residuals. To use it, SKAT_Null_Model or SKAT_Null_Model_MomentAdjust should have n.Resampling > 0.

Usage

	Get_Resampling_Pvalue(obj)

	Get_Resampling_Pvalue_1(p.value, p.value.resampling)


 

Arguments

obj	SKAT outcome object.
p.value	a numeric value of the SKAT p-value.
p.value.resampling	a vector of p-values from the resampled residuals.

Details

See SKAT_Null_Model

Value

p.value	the resampling p-value. It is computed as (n1 +1)/(n+1), where n is the number of resampling (n.Resampling in SKAT_Null_Model or SKAT_Null_Model_MomentAdjust), and n1 is the number of resampled residual p-values smaller than the original sample p-value.
is_smaller	a logical value indicates whether the resampling p-value should be smaller. If n1=0, then it is TRUE, otherwise it is FALSE.

Author(s)

Seunggeun Lee

SKAT documentation built on Jan. 15, 2023, 5:10 p.m.