WCE implements a flexible method for modeling cumulative effects of time-varying exposures, weighted according to their relative proximity in time, and represented by time-dependent covariates. The current implementation estimates the weight function in the Cox proportional hazards model. The function that assigns weights to doses taken in the past is estimated using cubic regression splines.

Install the latest version of this package by entering the following in R:

`install.packages("WCE")`

Author | Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca>, Marie-Eve Beauchamp <marie-eve.beauchamp@clinepi.mcgill.ca>, Ryan Patrick Kyle <ryan.kyle@mail.mcgill.ca>, Michal Abrahamowicz <michal.abrahamowicz@mcgill.ca> |

Date of publication | 2015-01-14 01:59:06 |

Maintainer | Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca> |

License | GPL (>= 2) |

Version | 1.0 |

**checkWCE:** Verify that the arguments passed to the WCE function are in...

**coef.WCE:** Obtain estimated coefficients from WCE object

**drugdata:** Sample dataset for use with WCE package

**HR.WCE:** Obtain a hazard ratio (HR) from a WCE Cox proportional...

**knots.WCE:** Obtain the placement of the knots used for splines in WCE...

**plot.WCE:** Plot of the weight function(s) estimated by 'WCE'

**summary.WCE:** Method to summarize the results of a WCE object

**vcov.WCE:** Obtain variance-covariance matrix from WCE models

**WCE:** Fit weighted cumulative exposure models

**wce-package:** Weighted Cumulative Exposure Models

inst

inst/doc

inst/doc/WCE.pdf.asis

inst/doc/WCE.pdf

NAMESPACE

data

data/drugdata.RData

R

R/checkWCE.R
R/vcov.WCE.R
R/WCE.R
R/print.WCE.R
R/coef.WCE.R
R/HR.WCE.R
R/WCE.default.R
R/WCE.cox.R
R/summary.WCE.R
R/knots.WCE.R
R/WCE.data.frame.R
R/WCE-internal.R
R/plot.WCE.R
vignettes

vignettes/WCE.pdf.asis

MD5

build

build/vignette.rds

DESCRIPTION

man

man/knots.WCE.Rd
man/HR.WCE.Rd
man/wce-package.Rd
man/plot.WCE.Rd
man/summary.WCE.Rd
man/checkWCE.Rd
man/vcov.WCE.Rd
man/drugdata.Rd
man/coef.WCE.Rd
man/WCE.Rd
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