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WCE implements a flexible method for modeling cumulative effects of timevarying exposures, weighted according to their relative proximity in time, and represented by timedependent covariates. The current implementation estimates the weight function in the Cox proportional hazards model. The function that assigns weights to doses taken in the past is estimated using cubic regression splines.
Package details 


Author  MariePierre Sylvestre <mariepierre.sylvestre@umontreal.ca>, MarieEve Beauchamp <marieeve.beauchamp@clinepi.mcgill.ca>, Ryan Patrick Kyle <ryan.kyle@mail.mcgill.ca>, Michal Abrahamowicz <michal.abrahamowicz@mcgill.ca> 
Date of publication  20150114 01:59:06 
Maintainer  MariePierre Sylvestre <mariepierre.sylvestre@umontreal.ca> 
License  GPL (>= 2) 
Version  1.0 
Package repository  View on CRAN 
Installation 
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