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A flexible method for modeling cumulative effects of timevarying exposures, weighted according to their relative proximity in time, and represented by timedependent covariates. The current implementation estimates the weight function in the Cox proportional hazards model. The function that assigns weights to doses taken in the past is estimated using cubic regression splines.
Package details 


Author  MariePierre Sylvestre, MarieEve Beauchamp, Ryan Patrick Kyle, Michal Abrahamowicz 
Date of publication  20180808 19:20:02 UTC 
Maintainer  MariePierre Sylvestre <[email protected]> 
License  GPL (>= 2) 
Version  1.0.2 
Package repository  View on CRAN 
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