WCE: Weighted Cumulative Exposure Models

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WCE implements a flexible method for modeling cumulative effects of time-varying exposures, weighted according to their relative proximity in time, and represented by time-dependent covariates. The current implementation estimates the weight function in the Cox proportional hazards model. The function that assigns weights to doses taken in the past is estimated using cubic regression splines.

Author
Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca>, Marie-Eve Beauchamp <marie-eve.beauchamp@clinepi.mcgill.ca>, Ryan Patrick Kyle <ryan.kyle@mail.mcgill.ca>, Michal Abrahamowicz <michal.abrahamowicz@mcgill.ca>
Date of publication
2015-01-14 01:59:06
Maintainer
Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca>
License
GPL (>= 2)
Version
1.0

View on CRAN

Man pages

checkWCE
Verify that the arguments passed to the WCE function are in...
coef.WCE
Obtain estimated coefficients from WCE object
drugdata
Sample dataset for use with WCE package
HR.WCE
Obtain a hazard ratio (HR) from a WCE Cox proportional...
knots.WCE
Obtain the placement of the knots used for splines in WCE...
plot.WCE
Plot of the weight function(s) estimated by 'WCE'
summary.WCE
Method to summarize the results of a WCE object
vcov.WCE
Obtain variance-covariance matrix from WCE models
WCE
Fit weighted cumulative exposure models
wce-package
Weighted Cumulative Exposure Models

Files in this package

WCE
WCE/inst
WCE/inst/doc
WCE/inst/doc/WCE.pdf.asis
WCE/inst/doc/WCE.pdf
WCE/NAMESPACE
WCE/data
WCE/data/drugdata.RData
WCE/R
WCE/R/checkWCE.R
WCE/R/vcov.WCE.R
WCE/R/WCE.R
WCE/R/print.WCE.R
WCE/R/coef.WCE.R
WCE/R/HR.WCE.R
WCE/R/WCE.default.R
WCE/R/WCE.cox.R
WCE/R/summary.WCE.R
WCE/R/knots.WCE.R
WCE/R/WCE.data.frame.R
WCE/R/WCE-internal.R
WCE/R/plot.WCE.R
WCE/vignettes
WCE/vignettes/WCE.pdf.asis
WCE/MD5
WCE/build
WCE/build/vignette.rds
WCE/DESCRIPTION
WCE/man
WCE/man/knots.WCE.Rd
WCE/man/HR.WCE.Rd
WCE/man/wce-package.Rd
WCE/man/plot.WCE.Rd
WCE/man/summary.WCE.Rd
WCE/man/checkWCE.Rd
WCE/man/vcov.WCE.Rd
WCE/man/drugdata.Rd
WCE/man/coef.WCE.Rd
WCE/man/WCE.Rd