WCE implements a flexible method for modeling cumulative effects of time-varying exposures, weighted according to their relative proximity in time, and represented by time-dependent covariates. The current implementation estimates the weight function in the Cox proportional hazards model. The function that assigns weights to doses taken in the past is estimated using cubic regression splines.

Author | Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca>, Marie-Eve Beauchamp <marie-eve.beauchamp@clinepi.mcgill.ca>, Ryan Patrick Kyle <ryan.kyle@mail.mcgill.ca>, Michal Abrahamowicz <michal.abrahamowicz@mcgill.ca> |

Date of publication | 2015-01-14 01:59:06 |

Maintainer | Marie-Pierre Sylvestre <marie-pierre.sylvestre@umontreal.ca> |

License | GPL (>= 2) |

Version | 1.0 |

**checkWCE:** Verify that the arguments passed to the WCE function are in...

**coef.WCE:** Obtain estimated coefficients from WCE object

**drugdata:** Sample dataset for use with WCE package

**HR.WCE:** Obtain a hazard ratio (HR) from a WCE Cox proportional...

**knots.WCE:** Obtain the placement of the knots used for splines in WCE...

**plot.WCE:** Plot of the weight function(s) estimated by 'WCE'

**summary.WCE:** Method to summarize the results of a WCE object

**vcov.WCE:** Obtain variance-covariance matrix from WCE models

**WCE:** Fit weighted cumulative exposure models

**wce-package:** Weighted Cumulative Exposure Models

WCE

WCE/inst

WCE/inst/doc

WCE/inst/doc/WCE.pdf.asis

WCE/inst/doc/WCE.pdf

WCE/NAMESPACE

WCE/data

WCE/data/drugdata.RData

WCE/R

WCE/R/checkWCE.R
WCE/R/vcov.WCE.R
WCE/R/WCE.R
WCE/R/print.WCE.R
WCE/R/coef.WCE.R
WCE/R/HR.WCE.R
WCE/R/WCE.default.R
WCE/R/WCE.cox.R
WCE/R/summary.WCE.R
WCE/R/knots.WCE.R
WCE/R/WCE.data.frame.R
WCE/R/WCE-internal.R
WCE/R/plot.WCE.R
WCE/vignettes

WCE/vignettes/WCE.pdf.asis

WCE/MD5

WCE/build

WCE/build/vignette.rds

WCE/DESCRIPTION

WCE/man

WCE/man/knots.WCE.Rd
WCE/man/HR.WCE.Rd
WCE/man/wce-package.Rd
WCE/man/plot.WCE.Rd
WCE/man/summary.WCE.Rd
WCE/man/checkWCE.Rd
WCE/man/vcov.WCE.Rd
WCE/man/drugdata.Rd
WCE/man/coef.WCE.Rd
WCE/man/WCE.Rd
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