p_burden_single: p_burden_single

In ZIM4rv: Gene‐based Association Tests of Zero‐inflated Count Phenotype for Rare Variants

p_burden_single

Description

Compute the p-value for the burden test

This function takes a vector of weights, a data frame of rare variants and a matrix of Score statistics produced by U_fi_lmd for ZIP model or U_phi_mu4zinb for ZINB model to compute the p-value for the burden test.

Usage

p_burden_single(wt, G_rare, s)

Arguments

wt	a numeric vector containing weights for all variants
G_rare	a data frame containing data of rare variants
s	a matrix of the score statistics for each variant from each subject

Value

the p-value for the burden test

ZIM4rv documentation built on April 3, 2025, 7:39 p.m.