p_kernel_single: p_kernel_single

In ZIM4rv: Gene‐based Association Tests of Zero‐inflated Count Phenotype for Rare Variants

p_kernel_single

Description

Compute the p-value for the kernel test

This function takes a diagonal matrix of weights, a data frame of rare variants and a matrix of Score statistics produced by U_fi_lmd for ZIP model or U_phi_mu4zinb for ZINB model to compute the p-value for the kernel test.

Usage

p_kernel_single(wt_matrix2, G_rare, s)

Arguments

wt_matrix2	a diagonal matrix containing the squared weights for all variants
G_rare	a data frame containing data of rare variants
s	a matrix of the score statistics for each variant from each subject

Value

the p-value for the kernel test (ZIP-k)

ZIM4rv documentation built on April 3, 2025, 7:39 p.m.