A simulated clinical trial based on the design of the Studies of Left Ventricular Dysfunction Trial (SOLVD-T), a placebo-controlled trial of the angiotensin-converting-enzyme inhibitor enalapril for patients with congestive heart failure.
A data frame with 2569 observations on the following 12 variables.
indicator for enalapril group
age at baseline (centered and scaled)
pulse at baseline (centered and scaled)
lymphocyte count at baseline (centered and scaled)
left ventricular ejection fraction at baseline (centered and scaled)
simulated vector of random uniform variables
indicator whether New York Heart Association score greater than 2
indicator whether cardiothoracic ratio is greater than 0.5
creatinine at baseline (centered and scaled)
sodium at baseline (centered and scaled)
time to death or hospitalization in days
indicator whether censored (1) or an event (0)
indicator whether current smoker
Simulated data set based on the clinical study reported by: Yusuf, S. et al. (1991). Effect of Enalapril on Survival in Patients with Reduced Left-Ventricular Ejection Fractions and Congestive-Heart-Failure. NEJM 325:293-302.
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