aop: Adverse Outcome Pathway Analysis

Provides tools for analyzing adverse outcome pathways (AOPs) for pharmacological and toxicological research. Functionality includes the ability to perform causal network analysis of networks developed in and exported from Cytoscape or existing as R graph objects, and identifying the point of departure/screening/risk value from concentration- response data.

AuthorLyle D. Burgoon <Lyle.D.Burgoon@usace.army.mil>
Date of publication2016-12-05 18:28:47
MaintainerLyle D. Burgoon <Lyle.D.Burgoon@usace.army.mil>
LicenseCC0
Version1.0.0

View on CRAN

Functions

aop_backdoor Man page
aop_cytoscape Man page
aop_cytoscape-class Man page
bmr Man page
bmr-class Man page
bootstrap_metaregression Man page
calculate_confidence_and_median Man page
convert_aop_to_graph Man page
convert_cytoscape_to_aop Man page
getAOPNodeName Man page
getAOPNodeName,aop_cytoscape-method Man page
internal_model_fits Man page
oxybenzone Man page
plot_metaregression_confidence_envelope Man page
plot_metaregression_spaghetti_plot Man page
plot_slope_analysis Man page
pod_envelope_analysis Man page
pod_slope_analysis Man page
slope_pod_analysis Man page

Files

aop
aop/inst
aop/inst/NEWS
aop/inst/extdata
aop/inst/extdata/steatosis_aop.png
aop/inst/extdata/steatosis_aop_json.cyjs
aop/inst/doc
aop/inst/doc/aop.Rmd
aop/inst/doc/concentration-response_analysis.R
aop/inst/doc/aop.R
aop/inst/doc/concentration-response_analysis.html
aop/inst/doc/aop.html
aop/inst/doc/concentration-response_analysis.Rmd
aop/inst/unitTests
aop/inst/unitTests/test_functions.R
aop/tests
aop/tests/runTests.R
aop/NAMESPACE
aop/data
aop/data/oxybenzone.rda
aop/R
aop/R/pod_analysis.R aop/R/aop_graph_analysis.R aop/R/aopCytoscape_Class.R aop/R/bmr_Class.R aop/R/aop_cytoscape_methods.R
aop/vignettes
aop/vignettes/aop.Rmd
aop/vignettes/concentration-response_analysis.Rmd
aop/README.md
aop/MD5
aop/build
aop/build/vignette.rds
aop/DESCRIPTION
aop/man
aop/man/internal_model_fits.Rd aop/man/pod_envelope_analysis.Rd aop/man/convert_aop_to_graph.Rd aop/man/pod_slope_analysis.Rd aop/man/bmr-class.Rd aop/man/aop_backdoor.Rd aop/man/aop_cytoscape-class.Rd aop/man/oxybenzone.Rd aop/man/calculate_confidence_and_median.Rd aop/man/plot_metaregression_spaghetti_plot.Rd aop/man/aop_cytoscape-methods.Rd aop/man/slope_pod_analysis.Rd aop/man/convert_cytoscape_to_aop.Rd aop/man/bootstrap_metaregression.Rd aop/man/plot_slope_analysis.Rd aop/man/plot_metaregression_confidence_envelope.Rd

Questions? Problems? Suggestions? or email at ian@mutexlabs.com.

Please suggest features or report bugs with the GitHub issue tracker.

All documentation is copyright its authors; we didn't write any of that.