beam.select: Edge selection with multiple testing and error control

Description Usage Arguments Details Value Author(s) References

View source: R/beam.select.r

Description

Infer graphical structures by multiple testing

Usage

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beam.select(object, thres = 0.1, method = "BH",
return.only = c(object@return.only, "adj"))

Arguments

object

An object of class beam-class.

thres

numeric. Threshold to be applied on adjusted tail probabilities.

method

character. Method to use for multiple comparison adjustment of tail probabilities.

return.only

character. Quantities to be returned.

Details

The argument method allows to adjust the tail probabilities obtained from the null distributions of the Bayes factors for multiple comparisons. Possible choices are: "holm", "bonferroni", "BH", "BY" and "HC". Apart from "HC", these are passed onto the R function p.adjust from package stats and we refer the user to its documentation for details. The method "HC" provides an optimal decision threshold based on the Higher Criticism score which is computed using the R function hc.thresh from package fdrtool. Again, we refer to the associated documentation for details.

The argument return.only allows to decide which quantities have to be in the output: it could be any subvector of c('cor', 'BF', 'prob', 'adj') (provided that the requested quantities have been computed in the beam object, except for adjusted probabilities). It can also be set to NULL: in this case, only the selected edges will be returned without any additional information. The default value for this argument are the columns present in the beam object plus the adjusted probabilities.

Value

An object of class beam.select-class

Author(s)

Gwenael G.R. Leday and Ilaria Speranza

References

Drton, M., & Perlman, M. D. (2007). Multiple testing and error control in Gaussian graphical model selection. Statistical Science, 430-449.
Goeman, J. J., & Solari, A. (2014). Multiple hypothesis testing in genomics. Statistics in medicine, 33(11), 1946-1978.
Donoho, D., & Jin, J. (2015). Higher criticism for large-scale inference, especially for rare and weak effects. Statistical Science, 30(1), 1-25.
Klaus, B., & Strimmer, K. (2012). Signal identification for rare and weak features: higher criticism or false discovery rates?. Biostatistics, 14(1), 129-143.


beam documentation built on July 1, 2020, 10:23 p.m.