blindrecalc: Blinded Sample Size Recalculation

Computation of key characteristics and plots for blinded sample size recalculation. Continuous as well as binary endpoints are supported in superiority and non-inferiority trials. See Baumann, Pilz, Kieser (2022) <doi:10.32614/RJ-2022-001> for a detailed description. The implemented methods include the approaches by Lu, K. (2019) <doi:10.1002/pst.1737>, Kieser, M. and Friede, T. (2000) <doi:10.1002/(SICI)1097-0258(20000415)19:7%3C901::AID-SIM405%3E3.0.CO;2-L>, Friede, T. and Kieser, M. (2004) <doi:10.1002/pst.140>, Friede, T., Mitchell, C., Mueller-Veltern, G. (2007) <doi:10.1002/bimj.200610373>, and Friede, T. and Kieser, M. (2011) <doi:10.3414/ME09-01-0063>.

Getting started

Package details

AuthorLukas Baumann [aut, cre] (<>), Maximilian Pilz [aut] (<>), Institute of Medical Biometry - University of Heidelberg [cph]
MaintainerLukas Baumann <>
LicenseMIT + file LICENSE
Package repositoryView on CRAN
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blindrecalc documentation built on Oct. 4, 2023, 5:06 p.m.