# toer.ChiSquare: Type I Error Rate In blindrecalc: Blinded Sample Size Recalculation

 toer,ChiSquare-method R Documentation

## Type I Error Rate

### Description

Computes the type I error rate of designs with blinded sample size recalculation or of fixed designs for one or several values of the nuisance parameter.

### Usage

```## S4 method for signature 'ChiSquare'
toer(
design,
n1,
nuisance,
recalculation,
allocation = c("exact", "approximate", "kf_approx"),
...
)
```

### Arguments

 `design` Object of class `ChiSquare` created by `setupChiSquare`. `n1` Either the sample size of the first stage (if `recalculation = TRUE` or the total sample size (if `recalculation = FALSE`). `nuisance` Value of the nuisance parameter in (0,1). For the Chi-Squared test this is the overall response rate. `recalculation` Should the sample size be recalculated after n1 n1 patients are recruited? `allocation` Whether the allocation ratio should be preserved exactly (`exact`) or approximately (`approximate` or `kf_approx`). `appproximate` uses the unrounded calculated sample size in the sample size recalculation, `kf_approx` rounds the sample size to the next integer. `...` Further optional arguments.

### Details

The method is only vectorized in either `nuisance` or `n1`.

### Value

One type I error rate value for every nuisance parameter and every value of n1.

### Examples

```  d <- setupChiSquare(alpha = 0.025, beta = 0.2, r = 1, delta = 0.2)
toer(d, n1 = c(10, 20), nuisance = 0.25, recalculation = TRUE)

```

blindrecalc documentation built on Nov. 18, 2022, 5:06 p.m.