fst_admix: Calculate FST for the admixed individuals

In bnpsd: Simulate Genotypes from the BN-PSD Admixture Model

Description

This function returns the generalized FST of the admixed individuals given their admixture proportion matrix, the coancestry matrix of intermediate subpopulations (or its special cases, see coanc_subpops parameter below), and optional weights for individuals. This FST equals the weighted mean of the diagonal of the coancestry matrix (see coanc_admix()). Below there are n individuals and k intermediate subpopulations.

Usage

fst_admix(admix_proportions, coanc_subpops, weights = NULL)

Arguments

admix_proportions	The n-by-k admixture proportion matrix
coanc_subpops	Either the k-by-k intermediate subpopulation coancestry matrix (for the complete admixture model), or the length-k vector of intermediate subpopulation FST values (for the BN-PSD model; assumes zero coancestries between subpopulations), or a scalar FST value shared by all intermediate subpopulations (also assumes zero coancestry between subpopulations).
weights	Optional length-n vector of weights for individuals that define their generalized FST (default uniform weights)

Details

As a precaution, function stops if both inputs have names and the column names of admix_proportions and the names in coanc_subpops disagree, which might be because these two matrices are not aligned or there is some other inconsistency.

Value

The generalized FST of the admixed individuals

Examples

# set desired parameters
# number of individuals
n_ind <- 1000
# number of intermediate subpopulations
k_subpops <- 10

# differentiation of intermediate subpopulations
coanc_subpops <- ( 1 : k_subpops ) / k_subpops

# construct admixture proportions
admix_proportions <- admix_prop_1d_linear(n_ind, k_subpops, sigma = 1)

# lastly, calculate Fst!!! (uniform weights in this case)
fst_admix(admix_proportions, coanc_subpops)

bnpsd documentation built on Aug. 25, 2021, 5:07 p.m.