enzymes: Liver Enzyme Data

In brglm2: Bias Reduction in Generalized Linear Models

Liver Enzyme Data

Description

Liver enzyme data collected from 218 patients with liver disease (Plomteux, 1980). The laboratory profile consists of enzymatic activity measured for four liver enzymes: aspartate aminotransferase (AST), alanine aminotransferase (ALT), glutamate dehydrogenase (GLDH) and ornithine carbamyltransferase (OCT).

Usage

enzymes

Format

A data frame with 218 rows and the following 6 columns:

• Patient: Patient ID

• Group: Four diagnostic groups were considered: acute viral hepatitis (1), persistent chronic hepatitis (2), aggressive chronic hepatitis (3) and post-necrotic cirrhosis (4).

• AST: Aspartate aminotransferase (in U/L)

• ALT: Alanine aminotransferase (in U/L)

• GLDH: Glutamate dehydrogenase (in U/L)

• OCT: Ornithine carbamyltransferase (in U/L)

Source

Data from Albert and Harris (1984, Chapter 5, Appendix I), and is also provided by the pmlr R package.

References

Albert A, Harris E K (1984). Multivariate Interpretation of Clinical Laboratory Data. Dekker: New York.

Plomteux G (1980). Multivariate analysis of an enzyme profile for the differential diagnosis of viral hepatitis. Clinical Chemistry, 26, 1897-1899.

brglm2 documentation built on Oct. 12, 2023, 1:07 a.m.