inst/doc/v06_append_pd_model.R

In campsismod: Generic Implementation of a PK/PD Model

## ----echo=FALSE, warning=FALSE, message=FALSE, results='hide'-----------------
EXPORT_PNG <- FALSE

## ----echo=TRUE, warning=FALSE, message=FALSE----------------------------------
library(campsismod)

## -----------------------------------------------------------------------------
pk_model <- model_suite$pk$`2cpt_fo`

## ----echo=TRUE, warning=FALSE, message=FALSE----------------------------------
pd_model <- model_suite$pd$effect_cmt_model
pd_model

## -----------------------------------------------------------------------------
pd_model <- pd_model %>% replace(Equation("PK_CONC", "A_CENTRAL/VC"))

## -----------------------------------------------------------------------------
pkpd_model <- pk_model %>% add(pd_model)
pkpd_model

## ----eval=EXPORT_PNG----------------------------------------------------------
#  library(campsis)
#  dataset <- Dataset(25) %>%
#    add(Bolus(time=0, amount=1000, compartment=1, ii=12, addl=2)) %>%
#    add(Observations(times=0:36))
#  results <- pkpd_model %>% simulate(dataset=dataset, seed=1)
#  shadedPlot(results, "CONC")

## ----eval=EXPORT_PNG----------------------------------------------------------
#  shadedPlot(results, "CONC")

## ----eval=EXPORT_PNG, echo=FALSE, results='hide'------------------------------
#  ggplot2::ggsave(filename="resources/pkpd_model_concentration.png", width=7, height=3, dpi=100)

## ----eval=EXPORT_PNG----------------------------------------------------------
#  shadedPlot(results, "EFFECT")

## ----eval=EXPORT_PNG, echo=FALSE, results='hide'------------------------------
#  ggplot2::ggsave(filename="resources/pkpd_model_effect.png", width=7, height=3, dpi=100)