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Functions to perform the following analyses: i) inferring epistasis from RNAi double knockdown data; ii) identifying gene pairs of multiple mutation patterns; iii) assessing association between gene pairs and survival; and iv) calculating the smallworldness of a graph (e.g., a gene interaction network). Data and analyses are described in Wang, X., Fu, A. Q., McNerney, M. and White, K. P. (2014). Widespread genetic epistasis among breast cancer genes. Nature Communications. 5 4828. <doi:10.1038/ncomms5828>.
Package details |
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Author | Audrey Qiuyan Fu and Xiaoyue Wang |
Maintainer | Audrey Q. Fu <audreyqyfu@gmail.com> |
License | GPL (>= 2) |
Version | 1.0.1 |
Package repository | View on CRAN |
Installation |
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