Chemical metrics of differentially expressed proteins in cancer and cell culture proteomics experiments. Data files in the package have amino acid compositions of proteins obtained from UniProt and >250 published lists of up- and down-regulated proteins in different cancer types and laboratory experiments. Functions are provided to calculate chemical metrics including protein length, grand average of hydropathicity (GRAVY), isoelectric point (pI), carbon oxidation state, and stoichiometric hydration state; the latter two are described in Dick et al. (2020) <doi:10.5194/bg-17-6145-2020>. The vignettes visualize differences of chemical metrics between up- and down-regulated proteins and list literature references for all datasets.
Package details |
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Author | Jeffrey Dick [aut, cre] (<https://orcid.org/0000-0002-0687-5890>), Ben Bolker [ctb] (<https://orcid.org/0000-0002-2127-0443>) |
Maintainer | Jeffrey Dick <j3ffdick@gmail.com> |
License | GPL (>= 2) |
Version | 1.1.2 |
URL | https://github.com/jedick/canprot |
Package repository | View on CRAN |
Installation |
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