calc_kel_double_tdm: Calculate elimination rate when given two TDM samples

In clinPK: Clinical Pharmacokinetics Toolkit

Calculate elimination rate when given two TDM samples

Description

Calculate elimination rate when given two TDM samples

Usage

calc_kel_double_tdm(
  dose = 1000,
  t = c(2, 11.5),
  dv = c(30, 10),
  tau = 12,
  t_inf = 1,
  V = NULL,
  steady_state = TRUE,
  return_parameters = FALSE
)

Arguments

dose	dose amount
t	time or time after dose, vector of size 2
dv	observed value, vector of size 2
tau	dosing interval
t_inf	infusion time
V	if specified, use that (empiric) value and don't estimate from data. Default 'NULL'.
steady_state	samples taken at steady state? Only influences AUCtau.
return_parameters	return all parameters instead of only kel?

Examples

calc_kel_double_tdm(dose = 1000, t = c(3, 18), dv = c(30, 10))

clinPK documentation built on May 29, 2024, 3:50 a.m.