clinfun: Clinical Trial Design and Data Analysis Functions

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Utilities to make your clinical collaborations easier if not fun. It contains functions for designing studies such as Simon 2-stage and group sequential designs and for data analysis such as Jonckheere-Terpstra test and estimating survival quantiles.

Author
Venkatraman E. Seshan
Date of publication
2016-11-30 16:28:51
Maintainer
Venkatraman E. Seshan <seshanv@mskcc.org>
License
GPL (>= 2)
Version
1.0.13

View on CRAN

Man pages

aucVardiTest
Two-Sample Tests for Growth Curves under Dependent Right...
calogrank
Survival curves analysis of covariance
coxphCPE
Gonen & Heller Concordance Probability Estimate
coxphERR
Heller Explained Relative Risk
coxphQuantile
Survival time quantile as a function of covariate
fedesign
Trial Designs Based On Fisher's Exact Test
gsdesign
Group Sequential Designs
gsdesign-internal
Group Sequential Designs Internal Functions
jonckheere.test
Exact/permutation version of Jonckheere-Terpstra test
ktau
Kendall's tau-b estimate
oc.twostage.bdry
Two-stage boundary operating characteristics
permlogrank
Permutation version of survdiff
ph2simon
Simon's 2-stage Phase II design
ph2single
Exact single stage Phase II design
power.ladesign
Power of k-sample rank test under Lehmann alternative
pselect
Probability of selection under pick the winner rule
ROCanalysis
Functions to plot and compare ROC curves.
roc.area.test
Nonparametric area under the ROC curve
roc.curve
Empirical ROC curve
roc.perm.test
Permutation test to compare ROC curve
roc.perm.test-internal
Group Sequential Designs Internal Functions
toxbdry
Stopping rule for toxicity monitoring
twostage.inference
Inference following a two-stage design for binary response

Files in this package

clinfun
clinfun/src
clinfun/src/fdwilcox.c
clinfun/src/lehmann.f
clinfun/src/stratperm.f
clinfun/src/jonckheere.f
clinfun/src/fedesign.f
clinfun/src/roccurve.f
clinfun/src/rshared.c
clinfun/src/coxphCPE.f
clinfun/src/fdnorm.c
clinfun/src/calogrank.f
clinfun/src/fpnorm.c
clinfun/src/jtpdf.f
clinfun/src/lrtest.f
clinfun/src/rocarea.f
clinfun/src/ph2simon.f
clinfun/src/ktau.f
clinfun/NAMESPACE
clinfun/R
clinfun/R/gsdesign.R
clinfun/R/coxphQuantile.R
clinfun/R/jonkheere.R
clinfun/R/permlogrank.R
clinfun/R/calogrank.R
clinfun/R/ph2single.R
clinfun/R/fedesign.R
clinfun/R/lehmann.R
clinfun/R/pselect.R
clinfun/R/roc.perm.test.R
clinfun/R/ktau.R
clinfun/R/coxphCPE.R
clinfun/R/roc.curve.R
clinfun/R/roc.area.test.R
clinfun/R/ph2simon.R
clinfun/R/toxbdry.R
clinfun/R/coxphERR.R
clinfun/R/aucVardiTest.R
clinfun/MD5
clinfun/DESCRIPTION
clinfun/man
clinfun/man/ph2simon.Rd
clinfun/man/power.ladesign.Rd
clinfun/man/jonckheere.test.Rd
clinfun/man/twostage.inference.Rd
clinfun/man/ktau.Rd
clinfun/man/roc.perm.test-internal.Rd
clinfun/man/aucVardiTest.Rd
clinfun/man/roc.perm.test.Rd
clinfun/man/roc.area.test.Rd
clinfun/man/ph2single.Rd
clinfun/man/calogrank.Rd
clinfun/man/ROCanalysis.Rd
clinfun/man/toxbdry.Rd
clinfun/man/pselect.Rd
clinfun/man/fedesign.Rd
clinfun/man/permlogrank.Rd
clinfun/man/gsdesign.Rd
clinfun/man/gsdesign-internal.Rd
clinfun/man/roc.curve.Rd
clinfun/man/coxphCPE.Rd
clinfun/man/coxphERR.Rd
clinfun/man/coxphQuantile.Rd
clinfun/man/oc.twostage.bdry.Rd
clinfun/INDEX
clinfun/CHANGES