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Colocalisation analysis tests whether two traits share a causal genetic variant in a specified genomic region. Proportional testing for colocalisation has been previously proposed [Wallace (2013) <doi:10.1002/gepi.21765>], but is reimplemented here to overcome barriers to its adoption. Its use is complementary to the fine- mapping based colocalisation method in the 'coloc' package, and may be used in particular to identify false "H3" conclusions in 'coloc'.
Package details |
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Author | Chris Wallace [aut, cre] (<https://orcid.org/0000-0001-9755-1703>) |
Maintainer | Chris Wallace <chris.x.wallace@gsk.com> |
License | GPL (>= 3) |
Version | 0.9.1 |
Package repository | View on CRAN |
Installation |
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