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Fit Cox proportional hazards models containing both fixed and random effects. The random effects can have a general form, of which familial interactions (a "kinship" matrix) is a particular special case. Note that the simplest case of a mixed effects Cox model, i.e. a single random pergroup intercept, is also called a "frailty" model. The approach is based on Ripatti and Palmgren, Biometrics 2002.
Package details 


Author  Terry M. Therneau [aut, cre] 
Maintainer  Terry M. Therneau <therneau@mayo.edu> 
License  LGPL2 
Version  2.216 
Package repository  View on CRAN 
Installation 
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