coxmeMlist: Coxme variance function

In coxme: Mixed Effects Cox Models

Coxme variance function

Description

This variance function accepts a list of matrices, which define a correlation structure for a coxme fit.

Usage

coxmeMlist(varlist, rescale = FALSE, pdcheck = TRUE, positive = TRUE)

Arguments

varlist	a list containing one or more matrix or bdsmatrix objects.
rescale	if TRUE, each input matrix is rescaled to have a diagonal of 1. (Kinship matrices for instance are often generated with a diagonal of .5 and would be multiplied by 2).
pdcheck	check each matrix to ensure that it is positive definite
positive	constrain coefficients to be positive. This may also be a vector of the same length as varlist

Details

If two matrices A and B were given, this fits the variance structure V= \sigma_1^2 A + \sigma_2^2 B, where the variances \sigma_1^2 and \sigma_2^2 are parameters that will be optimized by coxme, treating A and B as fixed.

Value

a coxme variance family object, used by coxme in the fitting process.

Author(s)

Terry Therneau

See Also

coxme

coxme documentation built on Sept. 11, 2024, 9:04 p.m.