dtpflow: Produce DTP flow diagram

In dtpcrm: Dose Transition Pathways for Continual Reassessment Method

Description

dtpflow will produce a flow diagram of the possible paths for the next three cohorts of subjects.

Usage

dtpflow(dtptable, cohort.labels = c('C1', 'C2', 'C3'))

Arguments

dtptable	a dataframe produced by calculate_dtps where cohort_sizes was of length 3.
cohort.labels	A vector of length 3, containing character strings for the cohort labels.

Details

The function will produce a visual flow diagram for the first three cohorts of the provided dataframe.

Examples

prior  <- c(0.1, 0.2, 0.5)
target <- 0.15
prev_tox <- c(0, 0, 0)
prev_dose <- c(2, 2, 2)
cohort_sizes <- c(2, 3, 3)

next_dose = applied_crm(prior = prior, target = target,
                        tox = prev_tox, level = prev_dose)$mtd

dose_func <- applied_crm

DTP = calculate_dtps(next_dose, cohort_sizes, prev_tox = prev_tox,
                      prev_dose = prev_dose, dose_func = applied_crm,
                      prior = prior, target = target)

dtpflow(dtptable = DTP, cohort.labels = c('C1', 'C2', 'C3'))

dtpcrm documentation built on Aug. 20, 2019, 5:23 p.m.