Clinical and follow-up data of breast cancer patients as collected in the Dutch Cancer Institute (NKI) in Amsterdam

Share:

Description

A data frame of 295 patients with breast cancer. The included variables are

patnr

Patient identification number

d

Survival status; 1 = death; 0 = censored

tyears

Time in years until death or last follow-up

diameter

Diameter of the primary tumor

posnod

Number of positive lymph nodes

age

Age of the patient

mlratio

Estrogen level?

chemotherapy

Chemotherapy used (yes/no)

hormonaltherapy

Hormonal therapy used (yes/no)

typesurgery

Type of surgery (excision or mastectomy)

histolgrade

Histological grade (Intermediate, poorly, or well differentiated)

vasc.invasion

Vascular invasion (-, +, or +/-)

crossval.clin.class

??

PICV

Estrogen level?

Format

A data frame, see data.frame.

References

van't Veer LJ, Dai HY, van de Vijver MJ, He YDD, Hart AAM, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R \& Friend SH (2002). Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530–536.

van de Vijver MJ, He YD, van 't Veer LJ, Dai H, Hart AAM, Voskuil DW, Schreiber GJ, Peterse JL, Roberts C, Marton MJ, Parrish M, Atsma D, Witteveen A, Glas A, Delahaye L, van der Velde T, Bartelink H, Rodenhuis S, Rutgers ET, Friend SH \& Bernards R (2002). A gene-expression signature as a predictor of survival in breast cancer. New England Journal of Medicine 347, 1999–2009.

van Houwelingen HC, Bruinsma T, Hart AAM, van't Veer LJ \& Wessels LFA (2006). Cross-validated Cox regression on microarray gene expression data. Statistics in Medicine 25, 3201–3216.