data.GST: The data of GSTs family interaction on cancer.

In etma: Epistasis Test in Meta-Analysis

Description

This data used the data from a meta-analysis included about 500 studies investigating the associations between GSTM1/GSTT1 and cancer, and saved the studies both reported the genotype of GSTM1 and GSTT1. Finally, there are 360 studies (375 populations) included in this data.

Usage

data("data.GST")

Format

A data frame with 375 observations on the following 12 variables.

Study

the first author and published year in included studies.

Ethnicity

the ethnicity of each population.

Country

the location of study.

Cancer

the subtype of cancer in each study.

case.GSTM1.0

the number of GSTM1 functional type in cases.

ctrl.GSTM1.0

the number of GSTM1 null type in cases (risk type).

case.GSTM1.1

the number of GSTM1 functional type in controls.

ctrl.GSTM1.1

the number of GSTM1 null type in controls (risk type).

case.GSTT1.0

the number of GSTT1 functional type in cases.

ctrl.GSTT1.0

the number of GSTT1 null type in cases (risk type).

case.GSTT1.1

the number of GSTT1 functional type in controls.

ctrl.GSTT1.1

the number of GSTT1 null type in controls (risk type).

References

Fang J, Wang S, Zhang S, Su S, Song Z, Deng Y, et al. (2013) Association of the Glutathione S-Transferase M1, T1 Polymorphisms with Cancer: Evidence from a Meta-Analysis. PLoS ONE 8(11): e78707. doi:10.1371/journal.pone.0078707

See Also

ETMA

Examples

data(data.GST)
head(data.GST)

etma documentation built on May 2, 2019, 8:30 a.m.