data.RAS: The data of RAS interaction on chronic kidney disease.

In etma: Epistasis Test in Meta-Analysis

Description

This used the data from a meta-analysis included about 100 studies investigating the associations between ACE insertion/deletion (I/D) and chronic kidney disease, and re-collected the studies included AGT M235T information. Finally, there are 34 studies included in this data.

Usage

data("data.RAS")

Format

A data frame with 34 observations on the following 12 variables.

Author

the first author in included studies.

Year

the published year in included studies.

Race

the race of each population.

Tyep

the subtype of chronic kidney disease in each study.

case.ACE.0

the number of I allele (rs4340) in cases.

case.ACE.1

the number of D allele (rs4340) in cases (risk allele).

ctrl.ACE.0

the number of I allele (rs4340) in controls.

ctrl.ACE.1

the number of D allele (rs4340) in controls (risk allele).

case.AGT.0

the number of M allele (rs699) in cases.

case.AGT.1

the number of T allele (rs699) in cases (risk allele).

ctrl.AGT.0

the number of M allele (rs699) in controls.

ctrl.AGT.1

the number of T allele (rs699) in controls (risk allele).

References

Lin C, Yang HY, Wu CC, Lee HS, Lin YF, Lu KC, et al. (2014) Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism Contributes High Risk for Chronic Kidney Disease in Asian Male with Hypertension: A Meta-Regression Analysis of 98 Observational Studies. PLoS ONE 9(1): e87604. doi:10.1371/journal.pone.0087604

See Also

ETMA

Examples

data(data.RAS)
head(data.RAS)

etma documentation built on May 2, 2019, 8:30 a.m.