constrMLE: Calculate constrained MLEs.

constrMLE.differenceR Documentation

Calculate constrained MLEs.

Description

Calculate the constrained maximum likelihood estimate from 2 independent binomials for the null hypothesis parameter (difference, ratio, or odds ratio of the two binomial parameters).

Usage

constrMLE.difference(X1, N1, X2, N2, delta0)

Arguments

X1

vector, number of events in group 1

N1

sample size in group 1

X2

vector, number of events in group 2

N2

sample size in group 2

delta0

null parameter value

Details

For details see Farrrington and Manning (1990) for the difference, Miettinen and Nurminen (1985) for the ratio, and Agresti and Min (2002) for the odds ratio.

Value

a list with the constrained MLE parameters, p1 and p2.

References

Agresti and Min 2002, Biostatistics 3:379-386.

Farrrington and Manning, Stat in Med 1990, 1447-1454.

Miettinen, 0. and Nurminen, M. (1985). Comparative analysis of two rates. Statistics in Medicine 4, 213-226.


exact2x2 documentation built on May 29, 2024, 10:51 a.m.