flan-package: Fluctuation analysis of mutant cell counts

Description Details Author(s) References


Statistical tools for fluctuation analysis of mutant cells counts.


Package: flan
Type: Package
Version: 0.7
Date: 2019-04-30
License: GPL

This package contains functions dedicated to :

- Distribution (dflan, pflan, qflan, and rflan): built as the classic distribution functions, like dnorm, pnorm, qnorm, and rnorm.

- Parametric estimation (mutestim): estimates of the parameters of interest, which are the mean number of mutations (or the mutation probability) and the fitness parameter.

- Parametric testing (flan.test): built as the classic test functions, like t.test.


Adrien Mazoyer, Rémy Drouilhet, Stéphane Despréaux, and Bernard Ycart

Maintainer: Adrien Mazoyer <[email protected]>


A. Mazoyer: Fluctuation analysis on mutation models with birth-date dependence Math. Biosci. (2018)

A. Mazoyer: Time inhomogeneous mutation models with birth-date dependence B. Math. Biol. (2017)

A. Mazoyer, R. Drouilhet, S. Despréaux and B. Ycart: flan: An R Package for Inference on Mutation Models. R Journal 9(1) (2017)

B. Ycart and N. Veziris: Unbiased estimates of mutation rates under fluctuating final counts. PLoS one 9(7) e101434 (2014)

B. Ycart: Fluctuation analysis with cell deaths. J. Applied Probab. Statist, 9(1):12-28 (2014)

B. Ycart: Fluctuation analysis: can estimates be trusted? One PLoS one 8(12) e80958 (2013)

A. Hamon and B. Ycart: Statistics for the Luria-Delbrück distribution. Elect. J. Statist., 6:1251-1272 (2012)

flan documentation built on May 9, 2019, 1:03 a.m.