Description Usage Format References
Bladder is an extension of Bladder0 to competing risks with 396 patients with bladder cancer from 21 centers, focusing on two competing endpoints, i.e, time to first bladder recurrence (an event of interest; Type 1 event) and time to death prior to recurrence (competing event; Type 2 event).
1 | data("bladder")
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A data frame with 396 observations on the following 13 variables.
OBS
Observation number
center
Institution number of 24 centers
surtime
Time to event
status
Event indicator(1=recurrence, 2=death before recurrence, 0=no event)
CHEMO
Treatment indicator representing chemotherapy(0=No, 1=Yes)
AGE
Age(0, <= 65 years; 1, > 65 years)
SEX
Sex(0=male, 1=female)
PRIORREC
Prior recurrent rate(0, primary; 1, <= 1/yr; 2, > 1/yr)
NOTUM
Number of tumors(0, single; 1, 2-7 tumors; 2, >= 8 tumors)
TUM3CM
Tumor size(0, < 3cm; 1, >= cm)
TLOCC
T cotegory(0=Ta, 1=T1)
CIS
Carcinoma in situ (0=No, 1=Yes)
GLOCAL
G grage(0=G1, 1=G2, 2=G3)
Sylvester, R., van der Meijden, A.P.M., Oosterlinck, W., Witjes, J., Bouffioux, C., Denis, L., Newling, D.W.W. and Kurth, K. (2006). Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. European Urology, 49, 466-477.
Ha, I.D., Sylvester, R., Legrand, C. and MacKenzie, G. (2011). Frailty modelling for survival data from multi-centre clinical trials. Statistics in Medicine, 30, 28-37.
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