Description Usage Arguments Details Value Author(s) Examples
View source: R/normalization.R
Returns glycans normalized with Reference Peak Normalization approach.
1 | refpeaknorm(d, grouping = FALSE, peak = NULL)
|
d |
data frame in long format containing glycan measurements |
grouping |
should data be normalized per groups |
peak |
glycan name to use as the reference peak. If |
Input data frame should have at least the following three columns:
- gid - representing a unique name of a sample
- glycan - representing glycan names
- value - representing measured values
and if the grouping argument is TRUE
it should also have column:
- groups - representing groupings (e.g. IgG1, IgG2 and IgG4)
Returns a data.frame with original glycan values substituted by normalized ones
Ivo Ugrina, Lucija Klarić
1 2 3 | data(mpiu)
mpiun <- refpeaknorm(mpiu)
head(mpiun)
|
From version 0.3 functions tanorm and glyco.outliers expect data frames
in long format.
# A tibble: 6 x 4
Plate gid glycan value
<int> <chr> <fctr> <dbl>
1 1 1_1 GP1 0.004197406
2 1 1_1 GP10 0.197161822
3 1 1_1 GP11 0.032123474
4 1 1_1 GP12 0.025134223
5 1 1_1 GP13 0.010406596
6 1 1_1 GP14 0.690281858
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