grantham-package: grantham: Calculate the Grantham Distance
In grantham: Calculate the Grantham Distance
grantham-package R Documentation
grantham: Calculate the Grantham Distance
Description
A minimal set of routines to calculate the Grantham distance \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1126/science.185.4154.862")}. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Author(s)
Maintainer: Ramiro Magno rmagno@pattern.institute (ORCID)
Authors:
Isabel Duarte iduarte@pattern.institute (ORCID)
Ana-Teresa Maia maia.anateresa@gmail.com (ORCID)
Other contributors:
University of Algarve [funder]
CINTESIS [funder]
Pattern Institute [copyright holder, funder]
See Also
Useful links:
grantham documentation built on Sept. 11, 2024, 8:20 p.m.
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| grantham-package | R Documentation |
grantham: Calculate the Grantham Distance
Description
A minimal set of routines to calculate the Grantham distance \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1126/science.185.4154.862")}. The Grantham distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Author(s)
Maintainer: Ramiro Magno rmagno@pattern.institute (ORCID)
Authors:
Isabel Duarte iduarte@pattern.institute (ORCID)
Ana-Teresa Maia maia.anateresa@gmail.com (ORCID)
Other contributors:
University of Algarve [funder]
CINTESIS [funder]
Pattern Institute [copyright holder, funder]
See Also
Useful links:
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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