grantham-package: grantham: Calculate the 'Grantham' Distance
In grantham: Calculate the 'Grantham' Distance
Description
Author(s)
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Description
A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Author(s)
Maintainer: Ramiro Magno ramiro.magno@gmail.com (ORCID)
Authors:
Isabel Duarte iduarte.scientist@gmail.com (ORCID)
Ana-Teresa Maia maia.anateresa@gmail.com (ORCID)
Other contributors:
CINTESIS [copyright holder, funder]
See Also
Useful links:
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Report bugs at https://github.com/maialab/grantham/issues
grantham documentation built on Jan. 7, 2022, 9:06 a.m.
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Description Author(s) See Also
Description
A minimal set of routines to calculate the 'Grantham' distance <doi:10.1126/science.185.4154.862>. The 'Grantham' distance attempts to provide a proxy for the evolutionary distance between two amino acids based on three key chemical properties: composition, polarity and molecular volume. In turn, evolutionary distance is used as a proxy for the impact of missense mutations. The higher the distance, the more deleterious the substitution is expected to be.
Author(s)
Maintainer: Ramiro Magno ramiro.magno@gmail.com (ORCID)
Authors:
Isabel Duarte iduarte.scientist@gmail.com (ORCID)
Ana-Teresa Maia maia.anateresa@gmail.com (ORCID)
Other contributors:
CINTESIS [copyright holder, funder]
See Also
Useful links:
Report bugs at https://github.com/maialab/grantham/issues
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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