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gsDesign: Group Sequential Design
Derives group sequential clinical trial designs and describes their properties. Particular focus on time-to-event, binary, and continuous outcomes. Largely based on methods described in Jennison, Christopher and Turnbull, Bruce W., 2000, "Group Sequential Methods with Applications to Clinical Trials" ISBN: 0-8493-0316-8.
Getting started
Package overview
README.md
A cure model calendar-based design"
A gentle introduction to group sequential design"
Basic time-to-event group sequential design using gsSurv"
Binomial SPRT"
Conditional error spending functions"
Conditional power and conditional error"
Graphical testing for group sequential design"
gsDesign package overview"
Integer sample size and event counts"
Multiplicity graphs"
Overview of survival endpoint design"
Spending function overview"
Two-sample normal sample size"
Vaccine efficacy trial design"
Browse package contents
Package details |
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| Author | Keaven Anderson [aut, cre] |
| Maintainer | Keaven Anderson <keaven_anderson@merck.com> |
| License | GPL (>= 3) |
| Version | 3.6.4 |
| URL | https://keaven.github.io/gsDesign/ https://github.com/keaven/gsDesign |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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