NEWS.md

In gsDesign: Group Sequential Design

gsDesign 3.6.0 (November, 2023)

Breaking changes

• gsSurv() and nSurv() have updated default values for T and minfup so that function calls with no arguments will run. Legacy code with T or minfup not explicitly specified could break (#105).

New features

• gsSurvCalendar() function added to enable group sequential design for time-to-event outcomes using calendar timing of interim analysis specification (#105).
• as_rtf() method for gsBinomialExact() objects added, enable RTF table outputs for standard word processing software (#102).

Improvements

• toBinomialExact() and gsBinomialExact(): fix error checking in bound computations, improve documentation and error messages (#105).
• print.gsSurv(): Improve the display of targeted events (very minor). The boundary crossing probability computations did not change. The need is made evident by the addition of the toInteger() function (#105).
• toInteger(): Fix the documentation and execution based on the ratio argument (#105).
• Update the vaccine efficacy, Poisson mixture model, and toInteger vignettes (#105).
• Standardize and improve roxygen2 documentation (#104).

gsDesign 3.5.0 (July, 2023)

• sfPower() now allows a wider parameter range (0, 15].
• toInteger() function added to convert gsDesign or gsSurv classes to integer sample size and event counts.
• toBinomialExact() function added to convert time-to-event bounds to exact binomial for low event rate studies.
• Added "A Gentle Introduction to Group Sequential Design" vignette for an introduction to asymptotics for group sequential design.
• as_table() and as_gt() methods for gsBinomialExact objects added, as described in the new "Binomial SPRT" vignette.
• In plot.ssrCP(), the hat syntax in the mathematical expression is revised, resolving labeling issues.
• ggplot2::qplot() usage replaced due to its deprecation in ggplot2 3.4.0.
• Link update for the gsDesign manual in the documentation, now directly pointing to the gsDesign technical manual bookdown project.
• Introduced a new hex sticker logo.

gsDesign 3.4.0 (October, 2022)

• Removed restriction on gsCP() interim test statistic zi (#63).
• Removed gMCP dependency. Updated vignettes and linked to vignettes in gMCPLite (#69).
• Added deprecation warning to hGraph() and suggested using gMCPLite::hGraph() instead (#70).
• Moved ggplot2 from Depends to Imports (#56).

gsDesign 3.3.0 (May, 2022)

• Addition of vignettes
• Demonstrate cure model and calendar-based analysis timing for time-to-event endpoint design
• Vaccine efficacy design using spending bounds and exact binomial boundary crossing probabilities
• Minor fix to labeling in print.gsProbability
• Fixed error in sfStep
• Updates to reduce R CMD check and other minor issues

gsDesign 3.2.2 (January, 2022)

• Use inherits() instead of is() to determine if an object is an instance of a class, when appropriate
• Correctly close graphics device in unit tests to avoid plot output file not found issues
• Minor fixes to hGraph() for multiplicity graphs
• Minor fix to nBinomial() when odds-ratio scale specified to resolve user issue
• Minor changes to vignettes

gsDesign 3.2.1 (July, 2021)

• Changed gt package usage in a vignette due to deprecated gt function
• Replied to minor comments from CRAN reviewer (no functionality impact)
• Minor update to DESCRIPTION citing Jennison and Turnbull reference

gsDesign 3.2.0 (January, 2021)

• Substantially updated unit testing to increase code coverage above 80%
• Updated error checking messages to print function where check fails
• Removed dependencies on plyr packages
• Updated github actions

gsDesign 3.1.1 (May, 2020)

• Vignettes updated
• Added hGraph() to support ggplot2 versions of multiplicity graphs
• Eliminated unnecessary check from sequentialPValue
• Targeted release to CRAN
• Removed dependencies on reshape2, plyr
• Updated continuous integration
• Updated license

gsDesign 3.1.0 (April, 2019)

• Addition of pkgdown web site
• Updated unit testing to from RUnit to testthat
• Converted to roxygen2 generation of help files
• Converted vignettes to R Markdown
• Added Travis-CI and Appveyor support
• Added sequentialPValue function
• Backwards compatible addition of spending time capabilities to gsDesign and gsSurv

gsDesign 3.0-5 (January, 2018)

• Registered C routines
• Fixed "gsbound"
• Replaced "array" by "rep" calls to avoid R CMD check warnings

gsDesign 3.0-4 (September, 2017)

• First Github-based release
• Cleaned up documentation for nBinomial1Sample()
• Updated documentation and code (including one default value for an argument) for nBinomial1Sample() to improve error handling and clarity
• Updated sfLDOF() to generalize with rho parameter; still backwards compatible for Lan-DeMets O'Brien-Fleming

gsDesign 3.0-3

• Introduced spending time as a separate concept from information time to enable concepts such as calendar-based spending functions. The only user function changed is the gsDesign() function and the change is the addition of the parameters usTime and lsTime; default behavior is backwards compatible.

gsDesign 3.0-2 (February, 2016)

• Simplified conditional power section of gsDesignManual.pdf in doc directory
• Corrected basic calculation in gsCP()
• Eliminated deprecated ggplot2 function opts()

gsDesign 3.0-1 (January, 2016)

• More changes to comply with R standards (in NAMESPACE - importFrom statements - and DESCRIPTION - adding plyr to imports) ensuring appropriate references.
• Deleted link in documentation that no longer exists (gsBinomialExact.Rd).
• Last planned RForge-based release; moving to Github.

gsDesign 3.0-0 (December, 2015)

• Updated xtable extension to meet R standards for extensions.
• Fixed xtable.gsSurv and print.gsSurv to work with 1-sided designs
• Update to calls to ggplot to replace show_guide (deprecated) with show.legend arguments where used in ggplot2::geom_text calls; no user impact
• Minor typo fixed in sfLogistic help file
• Cleaned up "imports" and "depends" in an effort to be an R "good citizen"
• Registered S3 methods in NAMESPACE

gsDesign 2.9-4

• Minor edit to package description to comply with R standards

gsDesign 2.9-3 (November, 2014)

• Added sfTrimmed as likely preferred spending function approach to skipping early or all interim efficacy analyses; this also can adjust bound when final analysis is performed with less than maximum planned information. Updated help(sfTrimmed) to demonstrate these capabilities.
• Added sfGapped, which is primarily intended to eliminate futility analyses later in a study; see help(sfGapped) for an example
• Added summary.spendfn() to provide textual summary of spending functions; this simplified the print function for gsDesign objects
• Added sfStep() which can be used to set an interim spend when the exact amount of information is unknown; an example of how this can be misused is provided in the help file
• Fixed rounding so that gsBoundSummary, xtable.gsSurv and summary.gsDesign are consistent for gsSurv objects

gsDesign documentation built on Nov. 12, 2023, 9:06 a.m.