event_diff: Considering the enrollment rate, failure rate, and...

In gsDesign2: Group Sequential Design with Non-Constant Effect

Considering the enrollment rate, failure rate, and randomization ratio, calculate the difference between the targeted number of events and the accumulated events at time x

Description

A helper function passed to uniroot()

Usage

event_diff(x, enroll_rate, fail_rate, ratio, target_event)

Arguments

x	Duration
enroll_rate	An enroll_rate data frame with or without stratum created by define_enroll_rate().
fail_rate	A fail_rate data frame with or without stratum created by define_fail_rate().
ratio	Experimental:Control randomization ratio.
target_event	The targeted number of events to be achieved.

Value

A single numeric value that represents the difference between the expected number of events for the provided duration (x) and the targeted number of events (target_event)

gsDesign2 documentation built on April 3, 2025, 9:39 p.m.