hctrial: hctrial: A package for designing phase 2 clinical trials...
In hctrial: Using Historical Controls for Designing Phase II Clinical Trials
Description
The hctrial package provides functions for designing phase 2 clinical trials that adjust for the
heterogeneity in the population.
Details
Two different ways are considered for designing a trial: based on known subgroups or based on historical data.
For initializing a stratified trial, use strat_start.
At interim, strat_interim should be used to adjust the trial.
At the end of the study, strat_end is used to adjust the trial again.
hist_start, hist_interim and hist_end work analogously, but are based on historical controls.
hctrial documentation built on May 1, 2019, 10:53 p.m.
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Description
The hctrial package provides functions for designing phase 2 clinical trials that adjust for the heterogeneity in the population.
Details
Two different ways are considered for designing a trial: based on known subgroups or based on historical data.
For initializing a stratified trial, use strat_start.
At interim, strat_interim should be used to adjust the trial.
At the end of the study, strat_end is used to adjust the trial again.
hist_start, hist_interim and hist_end work analogously, but are based on historical controls.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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