Man pages for iAdapt
Two-Stage Adaptive Dose-Finding Clinical Trial Design
| beta.ab | Generates parameters for the beta distribution # I don't... |
| dlt.prob | Calculate DLT probability corresponding to average nTTP for... |
| eff.stg1 | Generates efficacy outcomes for stage 1 when using binary... |
| eff.stg1.nTTP | Generates efficacy outcomes for stage 1 when using nTTP to... |
| get.thresh | Obtain average nTTP at each dose level |
| LRtox | Calculates likelihood of safety for single dose |
| LRtox.nTTP | Calculates likelihood of safety for single dose, using nTTP |
| nTTP.indiv.sim | Simulate full trial (both stages) x times when using nTTP to... |
| rand.prob | Calculates randomization probabilities and dose allocation... |
| rand.stg2 | Stage 2 Adaptive Randomization |
| rand.stg2.nTTP | Stage 2 Adaptive Randomization with nTTP to monitor toxicity |
| runExample | Launch Shiny app |
| safe.dose | Identify safe/acceptable doses from stage 1 based on observed... |
| safe.dose.nTTP | Identify safe/acceptable doses from stage 1 based on nTTP... |
| sim.plot | Generate plots for estimated percent allocation and response... |
| sim.summary | Visualize simulation results (Stages 1&2) |
| sim.trials | Simulate full trial (both stages) x times |
| sim.trials.nTTP | Simulate full trial (both stages) x times when using nTTP to... |
| TOX | Sample array of toxicity probabilities for 6 doses. Taken... |
| tox.profile | Generates DLTs and calculates the likelihood-ratio (LR) for... |
| tox.profile.nTTP | Generate nTTPs toxicity scores and the likelihhood-ratio (LR)... |
