Tran: Preprocessing - Tran

In iBATCGH: Integrative Bayesian Analysis of Transcriptomic and CGH Data

Description

This function computes the transition matrix corresponding to a specific matrix of latent states.

Usage

Tran(xi)

Arguments

xi	Matrix of estimated latent states

Details

The matrix of latent states must consider only 4 states:

1. Loss

2. Neutral

3. Gain

4. Amplification

Value

A 4 by 4 matrix with transition probabilities derived from the input matrix of latent states.

Author(s)

Alberto Cassese

References

Guha S, Li Y, Neuberg D. Bayesian hidden Markov modelling of array cgh data. JASA. 2008;103(482):485-497.

Examples

data(NCI_60)

X <- NCI_60$aCGH
xi <- InitXi(X)
tran <- Tran(xi)

iBATCGH documentation built on Oct. 23, 2020, 6:34 p.m.