# Preprocessing - Initialize matrix of latent states

### Description

This function takes a matrix of CGH data as the only argument and returns a crude estimate of the corresponding latent copy number states.

### Usage

1 |

### Arguments

`X` |
Matrix of aCGH data |

`bounds` |
Vector of threshold used to estimate the latent states |

### Details

Given as argument a vector of threshold bounds the function simply applies the thresholding to the data and groups them into four subsets. Each subset is associated to a specific latent state.

### Value

Return a matrix of estimated latent states, that could be used as input of the main function.

### Author(s)

Alberto Cassese

### References

Cassese A, Guindani M, Tadesse M, Falciani F, Vannucci M. A hierarchical Bayesian model for inference of copy number variants and their association to gene expression. Annals of Applied Statistics, 8(1), 148-175.

Cassese A, Guindani M, Vannucci M. A Bayesian integrative model for genetical genomics with spatially informed variable selection. Cancer Informatics.

### See Also

See Also `Tran`

### Examples

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