RFM mice were sacrificed and examined for lung tumors. This resulted in current status interval censored data: if the tumor was present, this implied left censoring and if no tumor was present this implied right censoring. Mice were placed in two different groups: conventional environment or germ free environment.
left side of observation interval
right side of observation interval
Group for mouse. Either ce (conventional environment) or ge (grem-free environment)
Hoel D. and Walburg, H.,(1972), Statistical analysis of survival experiments, The Annals of Statistics, 18, 1259-1294
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Loading required package: survival Loading required package: Rcpp Loading required package: coda Model: Cox PH Baseline: semi-parametric Call: ic_sp(formula = Surv(l, u, type = "interval2") ~ grp, data = miceData, bs_samples = 50) Estimate Exp(Est) Std.Error z-value p grpge 0.6785 1.971 0.3219 2.108 0.03505 final llk = -76.56894 Iterations = 54 Bootstrap Samples = 50 WARNING: only 50 bootstrap samples used for standard errors. Suggest using more bootstrap samples for inference
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