HLA_typing_synthetic_LIS: Synthetic clinical-laboratory HLA typing table (HistoTrac...
In immunogenetr: A Comprehensive Toolkit for Clinical HLA Informatics

HLA_typing_synthetic_LIS

R Documentation

Synthetic clinical-laboratory HLA typing table (HistoTrac "Patient" layout).

Description

A larger, deliberately messy synthetic data set patterned on a real laboratory information system "Patient" table, with one individual per row. It is intended as realistic development and test data for HLA_columns_to_GLstring and related functions: the typing columns exercise the full range of wild-caught notation, including serologic values with and without a leading "w" (e.g. "w4", "4"), leading zeros ("06"), bare-asterisk molecular shorthand ("*17"), colon-delimited molecular alleles ("02:01"), blanks, and NAs. Both serologic (A1Cd:dq2cd) and molecular (mA1Cd:mDPB12cd) typings are present for the HLA-A, B, Bw, C, DRB1, DRB3/4/5, DQB1, DQA1, DPB1 and DPA1 loci.

Usage

data(HLA_typing_synthetic_LIS)

Format

A tibble with 63 rows and 53 columns:

PatientId, UNOSId, HospitalID, PhysicianID: Synthetic record identifiers.
firstnm, lastnm, DOB: Synthetic demographics (donors carry their donor ID in firstnm).
categoryCd, RaceCd, GenderCd, ABOCd, PatientTypeCd, StatusCd: Synthetic categorical fields.
A1Cd:dq2cd: Serologic HLA typing (A, B, Bw, Cw, DR, DRw, DQ), as character.
mA1Cd:mDPB12cd: Molecular HLA typing (A, B, C, DRB1, DRB3/4/5, DQA1, DQB1, DPA1, DPB1), as character.
UNOSCPRAAmt: Synthetic calculated PRA value.
UnacceptAntigenTxt, ModerateRiskAntibodyTxt, UNOSUnacceptAntigenTxt: Synthetic antibody text fields.

Details

Note that the molecular (m...) columns deliberately contain a mix of true molecular values (e.g. "31:01") and serologic values (e.g. "w6"): the source laboratory historically recorded serologic typing in the molecular columns, so this captures that real-world mixed-nomenclature-within-a-column case.

All identifiers, names and dates are synthetic.