iq: Protein Quantification in Mass Spectrometry-Based Proteomics

An implementation of the MaxLFQ algorithm by Cox et al. (2014) <doi:10.1074/mcp.M113.031591> in a comprehensive pipeline for processing proteomics data in data-independent acquisition mode (Pham et al. 2020 <doi:10.1093/bioinformatics/btz961>). It offers additional options for protein quantification using the N most intense fragment ions, using all fragment ions, and a wrapper for the median polish algorithm by Tukey (1977, ISBN:0201076160). In general, the tool can be used to integrate multiple proportional observations into a single quantitative value.

Package details

AuthorThang Pham [aut, cre, cph, ctb] (<https://orcid.org/0000-0003-0333-2492>), Alex Henneman [ctb] (<https://orcid.org/0000-0002-3746-4410>)
MaintainerThang Pham <t.pham@amsterdamumc.nl>
LicenseBSD_3_clause + file LICENSE
Version1.9.12
URL https://github.com/tvpham/iq
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("iq")

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iq documentation built on May 29, 2024, 8:40 a.m.