colon_cancer: Meta-analysis: Real World Evidence in metastatic colorectal...

colon_cancerR Documentation

Meta-analysis: Real World Evidence in metastatic colorectal cancer, comparing antiangiogenic treatments with chemotherapy

Description

Meta-analysis of 7 RCTs, 4 cRWE studies, and 2 matched sRWE studies evaluating progression-free survival (PFS) as a surrogate endpoint to overall survival (OS) in metastatic colorectal cancer (mCRC), comparing antiangiogenic treatments with chemotherapy.

Format

A dataframe with 13 rows and 6 columns. Each row represents study results, the columns are:

study

Author and year.

study_type

randomized clinical trial or comparative/single-arm real-world-evidence

pfs

logarithm of hazard ratios of progression-free survival

se_pfs

standard error of pfs

os

logarithm of hazard ratios of overall survival

se_os

standard error of os

Source

Wheaton L, Papanikos A, Thomas A, Bujkiewicz S. Using Bayesian Evidence Synthesis Methods to Incorporate Real-World Evidence in Surrogate Endpoint Evaluation. Medical Decision Making. 2023;43(5):539-552. doi:10.1177/0272989X231162852


jarbes documentation built on June 28, 2025, 1:07 a.m.

Related to colon_cancer in jarbes...