fnrpcr: Meta-Analysis: Variation in False-Negative Rate of Reverse...

fnrpcrR Documentation

Meta-Analysis: Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction–Based SARS-CoV-2 Tests by Time Since Exposure

Description

A dataset summarizing the variation in false-negative rates of reverse transcriptase polymerase chain reaction (RT-PCR)–based SARS-CoV-2 tests as a function of time since exposure.

Format

A data frame with 410 rows and 11 columns. Each row represents the results from a study. The columns include:

study

Name of the author conducting the study.

test

Type of testing performed.

day

Number of days since symptom onset.

day_min

Minimum number of days since symptom onset. Applicable for studies by Guo et al. and Kim et al.

day_max

Maximum number of days since symptom onset. Applicable for studies by Guo et al. and Kim et al.

n

Total number of tests conducted on a given day.

test_pos

Number of positive test results.

inconclusive

Number of inconclusive test results. Applicable for studies by Kujawski et al. and Danis et al.

nqp

Number of positive but non-quantifiable test results, where the viral load is below the quantification threshold of log10(1) copies/1000 cells.

pct_pos

Proportion of positive tests expressed as a percentage.

Source

Kucirka LM, Lauer SA, Laeyendecker O, Boon D, Lessler J. Variation in False-Negative Rate of Reverse Transcriptase Polymerase Chain Reaction-Based SARS-CoV-2 Tests by Time Since Exposure. Ann Intern Med. 2020 Aug 18;173(4):262-267. doi: 10.7326/M20-1495. Epub 2020 May 13. PMID: 32422057; PMCID: PMC7240870.


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