| lr_combine | R Documentation |
Combines (multiplies) likelihood ratios from two independent evidence sources using the Bayesian multiplication principle. This is used to integrate genetic and non-genetic evidence, or multiple non-genetic variables.
lr_combine(LRdatasim1, LRdatasim2)
LRdatasim1 |
A data.frame with columns |
LRdatasim2 |
A data.frame with columns |
Under the assumption of conditional independence of evidence given each hypothesis, the combined LR is the product of individual LRs:
LR_{combined} = LR_1 \times LR_2
This follows from Bayes' theorem and is valid when the evidence sources are conditionally independent given the hypothesis.
Important: Both inputs must be data.frames with the same
structure. If using output from sim_lr_genetic, first
convert it using lr_to_dataframe.
A data.frame with columns:
Unrelated: Product of LR values under H2
Related: Product of LR values under H1
The number of rows equals the minimum of the input data frames.
Marsico FL, et al. (2023). "Likelihood ratios for non-genetic evidence in missing person cases." Forensic Science International: Genetics, 66, 102891. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1016/j.fsigen.2023.102891")}
sim_lr_genetic for genetic LR simulations,
sim_lr_prelim for non-genetic LR simulations,
lr_to_dataframe for converting genetic simulations,
plot_lr_distribution for visualizing combined distributions.
# Simulate LRs from two different variables
lr_sex <- sim_lr_prelim("sex", numsims = 500, seed = 123)
lr_age <- sim_lr_prelim("age", numsims = 500, seed = 456)
# Combine the evidence
lr_combined <- lr_combine(lr_sex, lr_age)
head(lr_combined)
# Compare distributions
summary(log10(lr_sex$Related))
summary(log10(lr_combined$Related))
# Visualize combined distribution
plot_lr_distribution(lr_combined)
# Combining genetic and non-genetic evidence
library(forrel)
x <- linearPed(2)
x <- setMarkers(x, locusAttributes = NorwegianFrequencies[1:5])
x <- profileSim(x, N = 1, ids = 2)
# Simulate genetic LRs and convert to dataframe
lr_genetic <- sim_lr_genetic(x, missing = 5, numsims = 100, seed = 123)
lr_genetic_df <- lr_to_dataframe(lr_genetic)
# Simulate non-genetic LRs
lr_prelim <- sim_lr_prelim("sex", numsims = 100, seed = 123)
# Combine both sources
lr_total <- lr_combine(lr_genetic_df, lr_prelim)
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