View source: R/analyse_sigmoidal.R
| logistic | R Documentation |
Calculate a 4- or 5-parameter logistic (sigmoidal) curve. The 4-parameter
symmetric form is fit by analyse_kinetics() with method = "sigmoidal"
and shape = "symmetric" (default), and by stats::nls() via the
self-starting wrapper SSlogistic().
logistic(t, A, B, xmid, slope, asym = NULL)
t |
A numeric vector of the predictor variable (time). |
A |
A numeric parameter for the starting asymptote of the response variable. |
B |
A numeric parameter for the ending asymptote of the response variable. |
xmid |
A numeric parameter for the time at the inflection point (the
steepest point) of the curve, in units of the predictor variable |
slope |
A numeric parameter for the response rate |
asym |
A numeric parameter for the asymmetry index of the curve; the
fraction of the amplitude |
The 5-parameter Richards form is exported for advanced use directly with
stats::nls() but is not used by analyse_kinetics() due to convergence
instability. For asymmetric responses, prefer gompertz() /
gompertz_left(), which are more stable.
Both forms are re-parameterised from the Richards generalised logistic
model so xmid is the time at inflection and slope is the response rate
dx/dt at the inflection.
4-parameter (symmetric):
A + (B - A) / (1 + exp(-4 * slope * (t - xmid) / (B - A)))
5-parameter (asymmetric):
A + (B - A) / (1 + exp(-k * (t - xmid)))^(1 / v) with
v = -log(2) / log(asym) and k = 2 * slope * v / ((B - A) * asym).
The inflection is at t = xmid with dx/dt = slope and
y(xmid) = A + (B - A) * asym for any asym in (0, 1):
asym = 0.5 (v = 1) collapses to the 4-parameter form.
asym -> 0 gives an early-acceleration curve (inflection near A).
asym -> 1 gives a late-acceleration curve (inflection near B).
asym = 0.368 (1/e) approximates a right-inflection gompertz() curve.
asym = 0.632 (1 - 1/e) approximates a left-inflection
gompertz_left() curve.
A numeric vector of predicted values the same length as the
predictor variable t.
analyse_kinetics(), SSlogistic(), gompertz(),
gompertz_left(), sigmoidal_drift(), monoexponential()
## create an asymmetric logistic curve with random noise
set.seed(15)
t <- 1:60
x <- logistic(t, A = 10, B = 100, xmid = 30, slope = 4, asym = 0.3) +
rnorm(length(t), 0, 2)
data <- data.frame(t, x)
## 5-parameter fit with the self-starting wrapper
model <- nls(x ~ SSlogistic(t, A, B, xmid, slope, asym), data = data)
summary(model)
y <- predict(model, data)
if (requireNamespace("ggplot2", quietly = TRUE)) {
ggplot2::ggplot(data, ggplot2::aes(t, x)) +
theme_mnirs() +
ggplot2::geom_point() +
ggplot2::geom_line(ggplot2::aes(y = y))
}
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