View source: R/analyse_monoexponential.R
| monoexp_start | R Documentation |
Vector-level initialiser behind monoexp_init(), called directly by the
kinetics worker on the fit window. Profiles tau (and TD for the
4-parameter model) on a coarse grid and keeps the RSS-minimising start
(cf. biexp_start()). The model is linear in A and B once tau
and TD are held, so the asymptotes are solved by least squares at
every grid point at once. Point estimates from derivative changepoints
or log-linearisation are too sensitive to noise, overshoot, and plateau
data on real NIRS signals, and can strand nls with a singular gradient.
monoexp_start(x, t, fixed = list(), has_TD = FALSE)
x, t |
Numeric vectors of the response and time. |
fixed |
A named list of user-fixed parameter values, which narrow the grids and constrain the free estimates. |
has_TD |
Logical; include the time delay |
A named numeric vector of starting estimates in model order.
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