gen_profile: Generate protein ratio profile from spectrum quantification...
In mstherm: Analyze MS/MS Protein Melting Data

Description Usage Arguments Details Value

gen_profile takes a matrix of spectrum channel quantification values belonging to a protein and "rolls them up" into a vector of protein-level relative quantification values.

1	gen_profile(x, method = "sum", method.denom = "first")

`x`	matrix of spectrum quantification values, one row per spectrum and one column per channel
`method`	method to use to "roll up" spectrum values to protein level
`method.denom`	method used to determine ratio denominator, passed as the "method" argument to `abs_to_ratio`

The following methods for spectrum-to-protein conversion are supported:

"sum": use the sum of the Spectrum values for each channel
"median": use the median of the spectrum values for each channel
"ratio.median": Like "median", but values for each spectrum are first converted to ratios according to "method.denom" channel
"ratio.mean": Like "ratio.median" but using mean of ratios

A numeric vector of the same length as the number of matrix columns

mstherm documentation built on May 2, 2019, 9:31 a.m.