armd.wide: armd.wide Data (240 x 10)
In nlmeU: Datasets and Utility Functions Enhancing Functionality of 'nlme' Package

armd.wide

R Documentation

armd.wide Data (240 x 10)

Description

Data from Age-Related Macular Degeneration (ARMD) clinical trial

Format

The armd.wide data frame has 240 rows and 10 columns. Data are stored in wide format with each row corresponding to one subject.

subject: a factor with 240 levels 1, 2, 3, 4, 5, ..., 240
lesion: an integer vector with values 1, 2, 3, 4
line0: an integer vector with values ranging from 5 to 17
visual0: an integer vector with values of visual acuity measured at baseline ranging from 20 to 85
visual4: an integer vector with values of visual acuity measured at 4 weeks ranging from 12 to 84
visual12: an integer vector with values of visual acuity measured at 12 weeks ranging from 3 to 85
visual24: an integer vector with values of visual acuity measured at 24 weeks ranging from 5 to 85
visual52: an integer vector with values of visual acuity measured at 52 weeks from 4 to 85
treat.f: a factor with 2 levels Placebo, Active
miss.pat: a factor with 9 levels ----, ---X, --X-, --XX, -XX-, ...,XXXX

Details

The ARMD data arise from a randomized multi-center clinical trial comparing an experimental treatment (interferon-alpha) versus placebo for patients diagnosed with ARMD.

Source

Pharmacological Therapy for Macular Degeneration Study Group (1997). Interferon alpha-IIA is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration. Results of a prospective randomized placebo-controlled clinical trial. Archives of Ophthalmology, 115, 865-872.